One of the most frustrating parts of designing for the web versus print is the limitation of font choices. There are only a handful of fonts you can use that every visitor is guaranteed to have if you want to keep the text selectable. In print design, you don't have that unique problem - Just do your layout and send it to production or generate a PDF and all is well.
The alternative, of course, is to make images for each headline or block of text that you want to have in a typeface and insert them into your webpage. Ordinarily, that works well enough.